Friday, 23 November 2012

Developmental Dyslexia and the Cerebellum (Cerebellar Theory)


http://www.learningbreakthrough.com/learning-breakthrough-blog/entry/developmental-dyslexia-and-the-cerebellum-cerebellar-theory   The learning breakthrough programme


Developmental Dyslexia and the Cerebellum (Cerebellar Theory)

Posted by Guest on Saturday, 27 February 2010 in Dyslexia
Dyslexia is a learning disorder that manifests itself as a difficulty with reading, spelling and in some cases mathematics. It is separate and distinct from reading difficulties resulting from other causes, such as a non-neurological deficiency with vision or hearing, or from poor or inadequate reading instruction. It is estimated that dyslexia affects between 5% and 12% of the U.S. population in some degree and is thought to be the result of a neurological defect/difference, and though not an intellectual disability, a language disability, among others. It is also worth noting that most dyslexics who have Boder's Dysiedetic type, have attentional and spatial difficulties which interfere with the reading acquisition process as well.

Visuospatial Cognition and Theories of Developmental Dyslexia:
When we look at a scene we feel that we perceive the visual world in all its detail and richness. This experienced quality and effortlessness of vision masks the fact that scene perception is actually a highly complex cognitive process, which requires the explorative scanning by eye movements, the quick and accurate direction of attention, the anticipation of the consequences of actions, and the integration and comparison of current visual input with stored representations of previously viewed parts of the scene and knowledge of objects and their relationships. A number of striking visual illusions demonstrate that scene perception is in fact a rather fragile process that essentially builds upon assumptions about the visual world to optimally piece together observations from a number of fields of scientific study.
The leading theories on the topic of developmental dyslexia should not be viewed as competing, but instead be seen as a complementary set of theories trying to explain the underlying causes of a similar set of symptoms but from a variety of research perspectives and backgrounds.

Here is a great link for information on the history and theories of developmental dyslexia.

Cerebellar Theory:
One such theory that has gained note in the past decade is represented by the automaticity/cerebellar theory of dyslexia. Here the biological claim is that the cerebellum of people with dyslexia is mildly dysfunctional and that a number of cognitive difficulties ensue from this dysfunction.

For many years, developmental dyslexia was thought to be a problem related to language itself. However, with the arrival of neuroimaging tools and greater research into the relationship between dyslexia and balance, among other things, opinions began to shift. It has become clear to researchers that developmental dyslexia and the cerebellum are somehow related due to the function of the cerebellum matching the deficits in function associated with developmental dyslexia.

The cerebellum, more than many other areas of the brain, is engaged in processing and deciphering a constant series of "behind the scenes" events. It is forever multitasking in the background of our conscious mind. It is responsible for the sequencing of input, the automatization of tasks and skills, as well as the production and interpretation of verbal and written language. Since developmental dyslexia is defined by problems in these three exact areas, the hypothesis that the cerebellum was responsible, especially when coupled with revelatory neuroimaging studies, has gathered strength and wide acceptance as a promising area of study.

The cerebellum plays a critical role in overall brain function but has particular importance in reading and writing tasks. “Impairments of the cerebellum cause deficits in motor control such as posture and balance, and additional difficulties in achieving ‘automaticity’ of other learned skills” including skills that are related to reading and writing. The complicated issue is deciding where and how there is a “misfire” among neural pathways—a task that can be almost impossible without the use of sophisticated imaging equipment over a long span.

Dyslexia Treatment:
While these problems seem difficult to overcome and detection of the exact location of the impairment may never be known, this does not mean there are not options for those with developmental dyslexia. In fact, cerebellar dysfunction as a theory does not imply a sentence for those with developmental dyslexia to a life of failed reading attempts.  With concentrated effort on refining the neural pathways in the cerebellum, along with the sensory connections from the cerebellum to the other critical informational processing centers in the brain, the brain’s natural plasticity can be taken advantage of to establish better neuro-processing to help overcome developmental dyslexia as well as other processing-based learning difficulties.

Nothing about the brain is static. It is always on, always at work; sending, receiving, responding, interpreting. Accordingly, it is always handling input, although this input or the pathways it travels on may not be “optimized” for adequate processing. Neurological issues like these underlie learning challenges and indicate that specific disabilities likedevelopmental dyslexia may be addressed simply… with vestibular-based brain training exercises like those available in the Learning Breakthrough Program.

Sources
Rochelle, K., & Talcott, J. (2006). Impaired balance in developmental dyslexia? A meta-analysis of the contending evidence. Journal of Child Psychology & Psychiatry, 47(11), 1159-1166.

Cyril R Pernet, Jean Baptiste Poline, Jean Francois Demonet and Guillaume A Rousselet: BMC Neuroscience (in press) – Brain classification reveals the right cerebellum as the best biomarker of dyslexia.  http://www.biomedcentral.com/bmcneurosci/

dore website causes

http://www.dore.co.uk/learning-difficulties/dyslexia/what-causes-dyslexia/     website 
http://www.dore.co.uk/case-studies/emily-halse/      case study


causes of dyslexia
It’s generally agreed that dyslexia can ‘run in the family’. It might be there in your genes, but exactly how and if it will show itself varies considerably from individual to individual.
Sometimes dyslexia can be attributed to a wide range of environmental factors, like birth trauma, problems during pregnancy, brain injuries, infections and toxins. Extensive research has identified chromosome abnormalities linked to reading and spelling. However, although considerable progress has been made, the exact mechanism that causes genes to contribute to the multi-faceted dyslexic condition is still unknown.

Over years of continuous study, numerous hypotheses have been put forward to explain the causes of dyslexia, but currently the most credible theory is to do with ‘automaticity’ and a small, but very important part of the brain called the cerebellum – your ‘skill centre’. Scientific research has identified that the cerebellum plays a major role in the process of learning and automating of skills, so that we can perform tasks ‘without thinking’.

However, the efficiency of the cerebellum varies between individuals.
When the ‘skill centre’ is not working as efficiently as it should, it does not communicate adequately with all the major centres of the brain, especially the cerebrum – your ‘thinking centre’. If the whole cerebellum is affected, then the result is problems in making a whole range of skills, like reading, writing, concentration and coordination become fully automatic. It can also affect balance, so learning to ride a bike becomes more difficult. When even the most mundane tasks become a problem, frustration and low self-esteem set in and, with it, accompanying behavioural and emotional difficulties. However the cerebellum is not always wholly affected, so a mix of different symptoms is usually the case.
Improving the efficiency of the cerebellum is fundamental to the Dore programme’s treatment of dyslexia. It’s the focus of the personalised, exercise-based programme created for each and every Dore participant, designed to achieve greater responsiveness in the skill centre and develop the links between it and other parts of the brain. It takes perseverance, dedication and a good deal of effort, but the results are worth it – Take a look at some case studies of people who says that the Dore Programme has helped change their lifes forever.

Wednesday, 21 November 2012

cognitive study


2008 S Heim et al. in a paper "Cognitive subtypes of dyslexia" describe how they compared different sub-groups of dyslexics in comparison with a control group. This is one of the first studies not to just compare dyslexics with a non dyslexic control, but to go further and compared the different cognitive sub groups with a non dyslexic control group.

read book online

http://www.amazon.co.uk/Dyslexia-Theory-Practice-Angela-Fawcett/dp/1861562101/ref=sr_1_1?s=books&ie=UTF8&qid=1353534688&sr=1-1

Neurobiology of dyslexia: a reinterpretation of the data


http://www.sciencedirect.com/science/article/pii/S0166223604003327


Trends in Neurosciences
Volume 27, Issue 12, December 2004, Pages 720–726

Neurobiology of dyslexia: a reinterpretation of the data

  • a Laboratoire de Sciences Cognitives et Psycholinguistique (EHESS/CNRS/ENS), 46 rue d'Ulm, 75230 Paris Cedex 5, France
  • b Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, UK
View full text
Theories of developmental dyslexia differ on how to best interpret the great variety of symptoms (linguistic, sensory and motor) observed in dyslexic individuals. One approach views dyslexia as a specific phonological deficit, which sometimes co-occurs with a more general sensorimotor syndrome. This article on the neurobiology of dyslexia shows that neurobiological data are indeed consistent with this view, explaining both how a specific phonological deficit might arise, and why a sensorimotor syndrome should be significantly associated with it. This new conceptualisation of the aetiology ofdyslexia could generalize to other neurodevelopmental disorders, and might further explain heterogeneity within each disorder and comorbidity between disorders.

Figures and tables from this article:
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Figure 1. Three causal models of the aetiology of developmental dyslexia. Ovals represent traits at the biological, cognitive and behavioural levels of description; arrows represent causal relationships between traits. Only a subset of all possible behavioural manifestations is represented. (a) Traits and relationships postulated by the phonological theory. (b) Traits and relationships postulated by the magnocellular theory. (c) The proposed model. Solid lines are used for core traits of developmental dyslexia, dashed lines for associated traits that are not necessarily present in each affected individual. Cases of comorbidity with other developmental disorders (e.g. specific language impairment) are not represented. Abbreviations: LGN, lateral geniculate nucleus; MGN, medial geniculate nucleus.
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Figure 2. A molecular layer ectopia in a dyslexic subject. Neurons and glia have escaped into the molecular layer of the cortex, through a breach in the external glial limiting membrane, to form an ectopia (between the two arrows). Scale bar, 250 μm. Micrograph kindly provided by Glenn D. Rosen.
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Figure 3. Neurobiology of developmental dyslexia. (a) Overall distribution of cortical ectopias observed across different dyslexic subjects (kindly provided by Glenn D. Rosen). (b) Brain areas activated in oral language tasks and exhibiting structural differences between dyslexics and controls. Areas in orange are supported by one published study, areas in red by more than one. Reproduced, with permission of Sage Publications, Inc., from Ref. [15](c) Brain areas activated during performance of the main phonological skills impaired in dyslexia: phonological awareness (yellow), rapid serial naming (red) and verbal short-term memory (blue). Reproduced, with permission, from Ref. [39].